rap1 antibody (Cell Signaling Technology Inc)
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rap1 antibody
Rap1 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rap1+antibody/pm41897459-76-62-64
Average 86 stars, based on 1 article reviews
Rap1 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rap1+antibody/pm41897459-76-62-64
Average 86 stars, based on 1 article reviews
rap1 antibody - by Bioz Stars,
2026-10
86/100 stars
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Magnetic Beads:Article Title: Glucotoxicity is mediated by cytoplasmic distribution of RAP1 in pancreatic β-cells. Article Snippet: Diabetes mellitus (DM) is a group of chronic metabolic disorders characterized by persistent hyperglycemia.. In our study, we analyzed the level and location of RAP1 changes in the development of β-cell dysfunction induced by glucotoxicity.. We employed three pancreatic β-cell lines, namely INS-1, 1.2B4, and NIT-1, as well as a streptozotocin-induced diabetes rat model. We demonstrate that after high glucose treatment, RAP1 is increased, probably through induction by AKT, allowing RAP1 to shuttle from the nucleus to the cytoplasm and activate NFκB signaling. Incubation:Article Title: Glucotoxicity is mediated by cytoplasmic distribution of RAP1 in pancreatic β-cells. Article Snippet: Diabetes mellitus (DM) is a group of chronic metabolic disorders characterized by persistent hyperglycemia.. In our study, we analyzed the level and location of RAP1 changes in the development of β-cell dysfunction induced by glucotoxicity.. We employed three pancreatic β-cell lines, namely INS-1, 1.2B4, and NIT-1, as well as a streptozotocin-induced diabetes rat model. We demonstrate that after high glucose treatment, RAP1 is increased, probably through induction by AKT, allowing RAP1 to shuttle from the nucleus to the cytoplasm and activate NFκB signaling. other:Article Title: GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner. Article Snippet: Article history: Pituitary adenylate cyclaseReceived 14 September 2008 Received in revised form 15 October 2008 Accepted 15 October 2008 Available online 21 October 2008 Article Title: Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis Article Snippet: These tissue sections were blocked for 10 minutes in a humidified chamber with the medical background Sniper reducing solution (BiocareMedical, Concord, CA), prior to incubation for 24 hours at 4°C, with a 1:200 dilution of one of the following primary antibodies: Article Title: Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1 Article Snippet: Antibodies were as follows: GRK2 (Millipore), Epac1, and Article Title: Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety Article Snippet: Then, the membranes were incubated with the following primary antibodies: Kv4.2 (1:1000, Neuromab, US), phospho-Kv4.2 (1:300, Thr 607 , Santa Cruz, US), phospho-Kv4.2 (1:1000, Ser 616 , MyBioSource, US), phospho-Kv4.2 (1:1000, Thr 602 , Bioss, China), Article Title: Multifunctional Mitochondrial Epac1 Controls Myocardial Cell Death Article Snippet: Primary antibodies for immunoblot were obtained from the following sources: Epac1 from Novus Biological, (1/1000, Cambridge, United Kingdom), RYR2 from Thermoscientific (1/1000), Calnexin from Enzo Life Science (1/1000), Bax, Bcl2, cleaved-caspase 3 and 9, cytochrome c, VDAC, GRP75, IP3R1, Rap1 (1/1000) and Cell-Signaling:Article Title: 3,6′-Disinapoyl Sucrose from Polygalae Radix Exerts Anti-Aging Effects via Modification of Telomeres, SIRT1/p53/p21 Pathway, Oxidative Stress and Autophagy Article Snippet: Mouse embryonic fibroblasts (NIH/3T3) were purchased from Meilun Biotechnology Co., Ltd., (Dalian, China). .. The first antibodies used in this experiment were as follows: SIRT1 antibody (Cell Signaling Technology, Shanghai, China, #9475, 1:1000), GFP antibody (Wuhan Sanying Biotechnology Co., Ltd., Wuhan, China, 50430-2-AP, 1:1000), p53 antibody (Hangzhou Huaan Biotechnology Co., Ltd., Hangzhou, China, HA722074, 1:1000), p21 antibody (Hangzhou Huaan Biotechnology Co., Ltd., Hangzhou, China, HA722065, 1:1000), TRF2 antibody (Cell Signaling Technology, Shanghai, China, #13136, 1:1000), and Article Title: 3,6'-Disinapoyl Sucrose from Polygalae Radix Exerts Anti-Aging Effects via Modification of Telomeres, SIRT1/p53/p21 Pathway, Oxidative Stress and Autophagy. Article Snippet: Mouse embryonic fibroblasts (NIH/3T3) were purchased from Meilun Biotechnology Co., Ltd., (Dalian, China). .. The first antibodies used in this experiment were as follows: SIRT1 antibody (Cell Signaling Technology, Shanghai, China, #9475, 1:1000), GFP antibody (Wuhan Sanying Biotechnology Co., Ltd., Wuhan, China, 50430-2-AP, 1:1000), p53 antibody (Hangzhou Huaan Biotechnology Co., Ltd., Hangzhou, China, HA722074, 1:1000), p21 antibody (Hangzhou Huaan Biotechnology Co., Ltd., Hangzhou, China, HA722065, 1:1000), TRF2 antibody (Cell Signaling Technology, Shanghai, China, #13136, 1:1000), and |